Sleep Apnea as an Independent Risk Factor for All-Cause Mortality: The Busselton Health Study PMC


Although uncommon, it is possible to die during sleep from untreated obstructive sleep apnea. Observational research has found that OSA increases a person’s risk of sudden death. This risk is believed to be higher in people of older age, in people with a critical illness, and in people with severe OSA. The Busselton Health Study is an ongoing representative and comprehensive survey of residents in the Shire of Busselton in the South-West region of Western Australia. The survey invites the participation of all individuals on the Commonwealth electoral roll. Electoral registration is compulsory for Australians ≥ 18 years of age.


For some people, treating the underlying cause of CSA can reduce or resolve breathing problems during sleep. Reestablishing normal breathing patterns may help enhance sleep quality and reduce other symptoms and complications of CSA. In the same study, the benefits of CPAP therapy pop over to these guys were seen at follow-up after one year and after three years. Other research over a period of up to seven years also found a lower risk of death in people with OSA who regularly used a CPAP machine. Tell a doctor if you wake up tired or with a headache or feel depressed.

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Indeed, we found age, study quality, publication year and the continent of the study population to significantly impact the variation of the pooled estimates. Lastly, although this meta-analysis included studies representative of five continents, including North America, Australia, Europe, Asia and South America, we were unable to identify any studies from Africa. There is a need for further research to confirm if the association between OSA and mortality remains true in populations not represented in our meta-analysis. Two authors (ESH and AES) screened titles and abstracts of the studies for inclusion eligibility independently. After screening initial articles, ESH and AES manually screened full-text articles for continued inclusion criteria.

Full search terms used in this study are presented in online supplemental table 2. In summary, search terms included Medical Subject Headings with combinations of ‘sleep apnoea, obstructive’ and ‘death, sudden and ‘cardiac death’’. We screened reference lists of identified navigate to these guys articles for potential eligibility as well. We did not impose any limitations related to the date of publication, language or geographical location. If the sleep study finds that your breathing is frequently disrupted during the test, you may be diagnosed with sleep apnea.

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The present systematic review and meta-analysis estimate the risk of all-cause and cardiovascular mortality in individuals with OSA. Objectives Over 1 billion individuals worldwide experience some form of sleep apnoea, and this number is steadily rising. Obstructive sleep apnoea (OSA) look at this can negatively influence one’s quality of life and potentially increase mortality risk. However, the association between OSA and mortality has not been reliably estimated. This meta-analysis estimates the risk of all-cause and cardiovascular mortality in individuals with OSA.

People with symptoms of sleep apnea, such as loud snoring, gasping during sleep, or excessive daytime sleepiness, should talk with their primary care doctor. The doctor can review their symptoms, sleep patterns, and overall health and recommend testing with a sleep study if necessary. The results of the present systematic review and meta-analysis suggest that individuals with OSA have a greater risk of all-cause sudden and cardiovascular death. Although Continuous Positive Airway Pressure is the go-to treatment, there are actually many ways to manage sleep apnea. Some solutions, such as Positional Therapy, can be done on your own and may be enough to improve mild cases. If you have severe sleep apnea, your doctor may ask that you undergo multiple types of treatment.

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