What Is The Main Cause Of Gout?:
Hard lumps of uric acid crystals (tophi) are first deposited in the joint (synovial) lining or cartilage or in bone near the joints and then under the skin around joints. Tophi can also develop in the kidney and other organs and under the skin on the ears. They commonly develop in the fingers, hands, feet, the Achilles tendon in the back of the lower leg, or around the elbows.
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Gout usually only involves one joint at a time, with the big toe most often affected. With proper treatment, you may never reach the final stage. A good rule of thumb is to eat moderate portions of healthy foods. If any additional questions occur to you during your medical appointments, don’t hesitate to ask. Here’s some information to help you get ready for your appointment, and what to expect from your doctor. In the most serious cases, surgery may be required to repair or replace a damaged joint.
But if gout is left untreated, the flares can start to occur more frequently and become more intense and debilitating, affecting more joints at the same time. During the periods between gout flares, patients often have no symptoms and feel totally fine. This pattern is highly suggestive of gout compared to many other types of arthritis. reference Anyone with high uric acid levels in their blood (hyperuricemia) can benefit from reducing high-purine foods. This may help to prevent gout in people with hyperuricemia who haven’t yet developed the disease. It may also help prevent existing gout from progressing and prevent other complications of hyperuricemia, such as kidney stones.
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But if the kidneys are not functioning well, or too much uric acid is produced, it can collect in the blood. The blood pressure’lowering drug losartan and the triglyceride-lowering drug fenofibrate both cause uric acid to be excreted in the urine. These medications additional reading can decrease uric acid slightly in people who are taking them for other reasons. After repeated flares, gout can become severe and persistent and may lead to permanent joint deformity. Usually, gout develops during middle age in men and after menopause in women.
If your uric acid level is above 6.8, the tophi will increase in size. If it is maintained at 6.8, they will stay about the same. But the lower you can get your uric acid on medication (say, if you get to 4 or 5), the more rapidly these deposits dissipate and disappear. Two common drugs used to treat uric acid are allopurinol and febuxostat. Gout is a painful form of arthritis that occurs when high levels of uric acid in the blood cause crystals to form and accumulate in and around a joint. Medication to reduce uric acid levels ‘ known as urate-lowering therapy (ULT) ‘ is usually recommended if you have recurrent attacks of gout or you have complications of gout.
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It can cause swelling and redness, and in some cases, it can lead to lumpy deposits that can be seen under the skin. Even though you don’t have symptoms during this stage, uric acid levels can build up in your blood and joints. A doctor may get redirected here prescribe medications to prevent future flares. Called tophi, these lumps are actually mounds of uric acid crystals. Tophi are most common in chronic gout patients, so you’d probably notice joint pain long before getting to this point.
The symptoms gradually disappear, joint function returns, and no symptoms appear until the next flare. However, if gout progresses, untreated flares tend to last longer, occur more frequently, and affect several joints. Some symptoms of gout can be like other health conditions. Make sure to see your healthcare provider for a diagnosis. Gout is caused by monosodium urate crystal deposits in the joints. It may also be caused by eating a lot of foods that are high in purines.
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Without treatment, gout flare-ups may last longer and happen more frequently. The main symptom of gout is intense joint pain that reduces to discomfort. Gout attacks can come on suddenly and may keep returning over time. This recurrence can slowly harm tissue in the area of inflammation, and the attacks can be extremely painful.
These flares are followed by long periods of remission’weeks, months, or years’without symptoms before another flare begins. Along with the big toe, joints that are commonly affected are the other toe joints, the ankle, and the knee. However, if you do develop gout, rest assured that the condition can be managed through a combination of medications, dietary changes, and alternative treatments. They can come up with a plan to reduce your chances of developing the condition. For instance, if you have risk factors for gout (such as a particular medical condition), they may consider that before recommending certain types of drugs. Decreased excretion of uric acid is the most common cause of gout.
However, many people develop antibodies that prevent this medication from continuing to work. Doctors may give immunosuppressive medications to prevent this from happening. Medications can lower blood levels of uric acid by decreasing the body’s production of uric acid or increasing the excretion of uric acid in the urine.