Zoloft Insomnia:
We used the GRADE approach to assessing the quality of the body of evidence. The findings are presented by antidepressant group (SSRI, TCA, other antidepressants). There were insufficient data to pool results for SSRIs compared with placebo so these were presented as a narrative description. Two review authors independently extracted data using a data extraction form. The extraction form was piloted before use and in the case of discrepancy, we consulted a third review author. Overall, the quality of the evidence was low due to a small number of people in the studies, and problems with how the studies were undertaken and reported.
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In other settings, TCA are known to have significant tolerability problems and are potentially fatal if taken in overdose (Wilson 2010). As such it currently inadvisable to recommend the use of a TCA for the short-term treatment of people with primary insomnia, even though this is an approach that seems to be commonly adopted in clinical practice. One meta-analysis of drugs used in treatment of chronic insomnia described seven studies that used antidepressants (doxepin, trazodone, trimipramine) to treat insomnia at doses used in depression (Buscemi 2007). Zoloft is an antidepressant that belongs to a group of drugs called selective serotonin reuptake inhibitors (SSRIs), which works by balancing serotonin levels in the brain and nerves. Zoloft is used to treat some types of depression, premenstrual dysphoric disorder (PMDD), social anxiety disorder (SAD), obsessive-compulsive disorder (OCD), panic disorder (PD), and post traumatic stress disorder (PTSD).
The mean number of participants per study was 125 with a minimum sample size of 16 and a maximum of 324. In keeping with MECIR conduct standard C37, we ran searches within 12 months of publication. The update searches (2016 and 2017) identified 1073 references and, after screening these, we identified 10 studies of interest.
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For others, the change in the chemical balance in their brains causes insomnia. Since it is an SSRI, Zoloft interferes with the brain’s chemistry, which may affect the sleep/wake cycle. Zoloft this content is classified as a selective serotonin reuptake inhibitor (SSRI) and works by increasing the availability of serotonin in the brain as well as changing the balance of serotonin receptors.
Insomnia can be caused by many factors, some better known, such as stress, anxiety, or an uncomfortable sleeping environment, and others, lesser known. For example, insomnia can also appear as a side effect of antidepressants, which frequently interfere with sleep physiology. Zoloft may cause insomnia, making it harder to fall asleep or stay asleep. For others, it may be ongoing ‘ lingering for several months or more ‘ requiring further treatment. Some studies indicate that variations in genes may play a role in the effectiveness and risk of side effects of specific antidepressants.
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After a week or two these side effects will go away for most people as their bodies get used to the medication. It’s possible to experience some of these side effects sporadically throughout the duration that you’re taking Zoloft, especially if your provider increases your dose. If they increase the dose, it will take a couple of weeks for your body to fully appreciate the new dose.
Unfortunately, what happens too often is that clinicians start these drugs for patients, typically in the face of a significant life stressor, and then continue the treatment long after it resolves. Sertraline, like other antidepressants, look at this may increase the risk of suicidal ideation and behavior in children, adolescents, and young adults with major depression. However, stopping antidepressant treatment abruptly or missing several doses can cause withdrawal-like symptoms.
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In some cases, people refer to these sleep habits as sleep hygiene. However, more hints in some cases, Zoloft may cause several different side effects.
Learn more about proven and effective treatment options for insomnia. If you need to drink alcohol, do so in moderation and only on the weekend. One study4 found that consuming caffeinated beverages after 2 PM can disrupt sleep even when consumed 12 hours before bedtime. Your doctor will start you off with a low dose of Zoloft to minimize side effects. The standard starting dose is 25-50mg daily, but this dosage depends on the reason for administration.
Note that you should not take disulfiram (a drug that helps treat alcohol use disorder) with Zoloft oral solution. This is because there is alcohol in this form of Zoloft, and taking it with disulfiram can cause certain side effects, such as nausea and vomiting. Having liver problems can cause Zoloft to build up in your body, which may increase your risk of side effects. Tell your doctor if you have liver problems before starting this drug. If you have closed-angle glaucoma and take Zoloft, you may have an increased risk of your condition worsening.