Vasomotor Symptoms During Menopause: A Practical Guide On Current Treatments And Future Perspectives PMC

Vms Menopause:

vms menopause

In South Korea, lung cancer is the fifth highest type of female cancer (7.2%), which affected 7,298 women in 2015 and has the highest mortality rate among female cancers. However, even in case of early endometrial cancer, the therapy is recommended 5 years after complete recovery. you can try these out For stages III and IV endometrial cancer, clear cell carcinoma, or serous papillary carcinoma patients, MHT is not recommended [120,121]. Venous thromboembolism has an annual disease frequency of 5.4 diseases per 100,000 adult populations in Europe and the US regardless of gender.

And women who quit smoking before they saw their 40th birthday experienced VMS symptoms to around the same extent as women who had never smoked. For example, research presented at the 2022 North American Menopause Society’s annual meeting found that Black women are more likely to experience severe hot flashes and night sweats. Findings from the Study of Women’s Health Across the Nation found that Black women have more severe and more frequent vasomotor symptoms, which include hot flashes and night sweats, when compared with white women.

The changing racial and ethnic composition of the U.S. population requires greater awareness of ethnic diversities and variations in VMS reporting for optimal healthcare delivery. All women will go through menopause, but not every woman experiences it the same way. We spoke with Laurie Jeffers, DNP, co-director of NYU Langone Health’s Center for Midlife Health and Menopause and sell member of HealthyWomen’s Women’s Health Advisory Council, and asked her what, exactly, we can expect before, during and after menopause. Other science-backed VMS remedies include following a Mediterranean diet and eating specific foods, including fruit. Exercise, and more specifically resistance training, may also have a positive effect on VMS, according to a 2019 Swedish study.

Even ones that have clinically been shown to be ineffective can produce some response, according to Sullivan. She tells patients they should be feeling better within a month if they try these dietary and supplemental remedies. And it’s always important to check in with your healthcare provider (HCP) before trying home remedies.

There is no reliable way of predicting when hot flashes will first start or stop. If you’ve had a hysterectomy, you may be able to take estrogen alone, but if you have a uterus, you will likely need to take progesterone and estrogen to avoid increasing your risk of cancer in the lining of your uterus (endometrial cancer). Your doctor will adjust your dose to the minimum amount required to ease your symptoms.

She cut back on sugar and caffeine, which she has discovered are triggers for her vasomotor menopause symptoms. Similar to standard-dose MHT, low-dose MHT is reported to be effective for treating VMS [16]. Hot flush, a common VMS, suddenly appears in the face and the upper body and spreads to the rest of the body. Anxiety, shivering, palpitation, or perspiration may occur alongside, and night sweat is linked to sleep disorder. Healthcare professionals can usually recognize VMS just from a description of your symptoms, your age, and how far along you are in the menopause process, per the Mayo Clinic. It’s not often that they will use a blood test to help establish the diagnosis.

vms menopause

Vasomotor symptoms (VMS), including hot flashes and night sweats, occur in as many as 68.5% of women as a result of menopause. While the median duration of these symptoms is 4 years, approximately 10% of women continue to experience VMS as many as 12 years after their final menstrual period. As such, VMS have a significant impact on the quality of life and overall physical health of women experiencing VMS, leading to their pursuance of treatment to alleviate these symptoms. advice Management of VMS includes lifestyle modifications, some herbal and vitamin supplements, hormonal therapies including estrogen and tibolone, and nonhormonal therapies including clonidine, gabapentin, and some of the serotonin and serotonin’norepinephrine reuptake inhibitors. The latter agents, including desvenlafaxine, have been the focus of increased research as more is discovered about the roles of serotonin and norepinephrine in the thermoregulatory control system.

Indirect evidence suggests that the serotonergic and noradrenergic systems, neurotransmitter systems commonly linked to depression, may be involved in the etiology of VMS,10-13, 66 raising the possibility that central nervous system processes contribute to both VMS and depression vulnerability. Vasomotor symptoms like hot flashes have plagued women for millennia, but we’re really only starting to understand them. NAMS recommends CE/BZA as an effective MHT for treatment of VMS and prevention of osteoporosis and fracture in menopausal women without an excised uterus and states that progestogen is not required as bazedoxifene protects the endometrium.

There is no reliable research finding about whether low-dose estrogen’progestogen combination therapy increases the risk of breast cancer. In case of long-term use of progestogen, there has been a report about the possibility of increasing the frequency of breast cancer occurrence. However, according to the E3N-EPIC cohort study conducted in France, there is a report about how natural progesterone use would not increase the risk of breast cancer. Therefore, the risk of breast cancer is expected to differ depending on the progestogen medicine [106].

To treat the symptoms of an overactive bladder, changes in lifestyles and bladder training are very important and are recommended as the primary treatment methods. The systemic ET shows a similar effect to a placebo with regard to the treatment of the symptoms of nocturia and urinary frequency, but it is more effective than a placebo for the treatment of symptoms. Combined administration of vaginal estrogen and antimuscarinic drug is more suitable, and topical estrogen is considered to play an important role in treating an overactive bladder. Hence, the combination therapy of an antimuscarinic drug and topical estrogen is the primary drug therapy for menopausal women with symptoms of an overactive bladder [44,45,46]. Topical ET was shown to be effective in preventing recurrent UTIs by recovering microbiological changes that occurred within the vagina after beginning menopause and by reducing vaginal acidity, but systemic ET was not effective for preventing recurrent UTIs [47].

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